MEND CENTER, MEDANTA, THE MEDICITY
Commonly Used Drugs in Diabetes
Metformin is a safe, well tolerated and time-tested drug, which does not cause low blood sugar when used alone. Some patients may lose weight with metformin. Minority of patients may have gastrointestinal side effects like diarrhea or nausea.
With or after meals.
The drug should be avoided in kidney failure and liver disease.
(Glimepiride, Glipizide, Gliclazide, Glibenclamide)
These drugs are well tolerated, however sometimes they can cause low blood sugar, dizziness, headache, Increased sweating,shivering, blurring of vision, weakness.
30 - 45 minutes before meals
The drug should be avoided in liver or kidney disease or with alcohol.
These drugs help in controlling post-meal blood-sugar and can cause mild side effects like indigestion, abdominal discomfort and flatulence
Immediately before meals or with the first bite
These drugs should be avoided in cases of malabsorption and liver disease.
These drugs are usually well tolerated and do not cause low blood sugar when used alone or with metformin, and are weight neutral.
Independent of meals
Severe kidney disease or past history of pancreas disorder.
These drugs are typically used as add on therapy. These drugs can cause water retention resulting in swelling of legs in some patients;they can also cause weight gain.
Independent of mealtime
The drug should be avoided in heart failure or liver disease.
Rosiglitazone is available in the market. It should be avoided in view of increased risk of heart attack.
Aspirin is usually well-tolerated; however upper abdominal discomfort and indigestion can occur especially when taken on empty stomach. Rarely can it cause anaemia and bleeding tendency form various sites. Special caution in patients with asthma and bleeding disorders.
the drug should be avoided in peptic ulcer and in patients with allergy to aspirin.
(Atorvastatin, Rosuvastatin Simvastatin)
These are usually safe drugs and well tolerated. In few patients these drugs can cause muscular pains and deranged liver enzymes.
Independent of meals
Liraglutide (Victoza)/ Exenatide (Byetta)
These are injectable preparations which help reducing blood sugar and also help loosing body weight. These may have mild gastrointestinal side effects
Victoza- once daily, independent of meal time / Byetta- twice daily -60 minutes before morning and evening meal.
Pancreatitis, long term alcohol use.
This document does not include all side effects or drug description, however provides you with the basic drug profile. In case you notice any new symptom after starting the drugs kindly stop the drug and contact us. Some of these drugs can be harmful in pregnancy. In case pregnancy occurs, it should be informed to your doctor immediately.